Q02156, PRKCE, MGC125656, PKCE, MGC125657, nPKC-epsilon, kinase
Actual product may vary
Q02156, PRKCE, MGC125656, PKCE, MGC125657, nPKC-epsilon, kinase
Q02156, PRKCE, MGC125656, PKCE, MGC125657, nPKC-epsilon, kinase
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Q02156, PRKCE, MGC125656, PKCE, MGC125657, nPKC-epsilon, kinase

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Catalog number 14518
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PKCε Protein, Active

Protein kinase Ce (PKCe) is one of the major protein kinase C isoforms of a family of serine/threonine protein kinases. Breakdown of phosphatidylinositol leads to formation of diacylglycerol and inositol triphophate, the former acting synergistically with Ca2+ to activate protein kinase C (PKC), resulting in translocation of the enzyme from cytosol to the membrane. Phosphorylation of proteins by PKC has been implicated as a pivotal regulatory element in signal transduction, cellular regulation, and with a high affinity to phorbol ester tumor promoters.

GenBank X65293

Active, N-terminal His6-tagged, recombinant PKCε, amino acids 2-end, for use in Kinase Assays.
Specifications
Expression SystemRecombinant enzyme expressed in Sf21 insect cells
Quantity10 μg
ProteinPKCε, active
Protein FormTruncated
RecombinantRecombinant
Purity or Quality Grade≥74%
SpeciesHuman
Protein TagN-terminal 6His
Formulationmg/mL of enzyme in 20 mM Tris/HCl pH 7.5, 1 mM EGTA, 1 mM EDTA, 0.02% Triton X-100, 5% glycerol, 1 mM PMSF, 10 mM benzamidine, 1 mM DTT. Frozen solution.
Molecular Weight (g/mol)84.6 kDa
Unit SizePK